1033-116 Optimizing exercise protocols for heart failure trials
نویسندگان
چکیده
منابع مشابه
Using exercise endpoints in heart failure trials: design considerations.
made by the individual clinician will not be based only on life expectancy calculations and risk of cerebral bleeding. Other clinical information (such as previous history of angioplasty or bypass surgery, previous administration of streptokinase, recent surgery, anticipated problems with vascular access etc.), patient's preference and many practical considerations (such as, for example, ongoin...
متن کاملEmerging Drug Therapies for Heart Failure
Heart failure is associated with high morbidity and mortality and is proving to be an economic burden in developing countries. A number of therapeutic agents are presently employed in heart failure; but they are not sufficient to control symptoms of heart failure. Moreover, the prevalence of chronic heart failure is progressively increasing and thus there is a continuing need to develop effecti...
متن کاملExercise in Chronic Heart Failure
Background. Exertional fatigue, which frequently limits exercise in patients with chronic heart failure, is associated with early anaerobic metabolism in skeletal muscle. The present study was designed to examine the skeletal muscle metabolic response to exercise in this disorder and determine the relation of reduced muscle blood flow and skeletal muscle biochemistry and histology to the early ...
متن کاملExercise training in heart failure
Chronic heart failure (CHF) is a common condition with a poor prognosis. It is associated with poor exercise tolerance and debilitating symptoms. These symptoms appear to be associated with pathophysiological changes that occur systemically in the patient with CHF. Exercise training in carefully selected patients has been shown to be safe and to improve exercise capacity. Many of the pathophysi...
متن کاملExercise training meta-analysis of trials in patients with chronic heart failure (ExTraMATCH).
OBJECTIVE To determine the effect of exercise training on survival in patients with heart failure due to left ventricular systolic dysfunction. DESIGN Collaborative meta-analysis. Inclusion criteria Randomised parallel group controlled trials of exercise training for at least eight weeks with individual patient data on survival for at least three months. Studies reviewed Nine datasets, totall...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(04)90717-6